Wednesday, 8 October 2025

NFL Week 6 Pick ‘Em: Can Lions outmuscle Chiefs on the road?

With the Buffalo Bills losing in Week 5 on Sunday Night Football, the Super Bowl odds have narrowed, with four teams having odds of +1000 or better, per the BetMGM online sportsbook.

With Week 6 here, there are several storylines to keep an eye on, but I’ll be watching the Kansas City Chiefs.

They are hosting the best offence in the league, the Detroit Lions. A win at home would push them to 3-3, and this could be the start of the Chiefs pushing back into that upper echelon of AFC teams.

Find my predictions for that game and more below.

New York Giants vs. Philadelphia Eagles

The Eagles have several high-profile players on the injury report, including running back Saquon Barkley, linebacker Jihaad Campbell, and guard Landon Dickerson.

While Barkley may play, I do question his effectiveness on a short week. Additionally, the injury to Dickerson is worrisome against a Giants pass rush that’s fourth in the league in pressures with 77.

PREDICTION: Giants +7.5 (-110)

New York Jets vs. Denver Broncos

The Broncos lead the league in pressures with 89, and the Jets have allowed a league-high 95 pressures.

That is not good news for the Jets.

PREDICTION: Broncos -7.5 (-105)

Indianapolis Colts vs. Arizona Cardinals

The Cardinals have lost three straight, and their only wins have come against the New Orleans Saints and Carolina Panthers.

Now, they’re on the road against the Colts, who average the second-most points per game at 32.6.

With this spread just under a touchdown, I’ll take the Colts.

PREDICTION: Colts -6.5 (-110)

Pittsburgh Steelers vs. Cincinnati Browns

The Browns have an excellent pass-rushing duo in Myles Garrett and Maliek Collins. Additionally, rookie quarterback Dillon Gabriel’s average time to throw in Week 5 was just 2.44 seconds.

The Steelers edge out a win, but between the Browns’ pass rush, their QB getting the ball out quickly, and a reliable running game, they’ll cover.

PREDICTION: Browns +5.5 (-110)

Carolina Panthers vs. Dallas Cowboys

At home this season, Panthers QB Bryce Young is 2-0. Now, he’ll take on a Cowboys defence that’s allowing 127.4 rushing yards (23rd in the NFL) and 284.6 passing yards (32nd) per game.

The Cowboys win, but the Panthers cover or force a push.

PREDICTION: Panthers +3 (-110)

Miami Dolphins vs. Los Angeles Chargers

The Chargers haven’t been playing well recently, and now they’re without star rookie RB Omarion Hampton, who was placed on injured reserve.

I’ll take the Dolphins at home against the spread.

PREDICTION: Dolphins +4.5 (-110)

Baltimore Ravens vs. Los Angeles Rams

This Ravens team is doomed. Whether they start Cooper Rush again or Tyler Huntley, they’re facing a Rams pass rush that’s fifth in the league in pressures with 76.

Another Ravens blowout loss feels imminent.

PREDICTION: Rams -7.5 (-110)

New Orleans Saints vs. New England Patriots

Coming off a massive win on Sunday Night Football against the Buffalo Bills, the Patriots are on a two-game win streak.

They also have one of the best run defences in the league, allowing just 85.6 yards per game.

They’ll handle the Saints on the road.

PREDICTION: Patriots -3.5 (-110)

Jacksonville Jaguars vs. Seattle Seahawks

The Jaguars play Cover-3 more than any other coverage, and versus that this season, Seahawks QB Sam Darnold has completed 68.8 per cent of his passes for 389 yards (8.1 yards per attempt) and three touchdowns.

The Seahawks have the better QB in this matchup.

I’ll take the point.

PREDICTION: Seahawks +1 (-110)

Las Vegas Raiders vs. Tennessee Titans

I’m sorry, but I can’t take the Raiders at -4.5, even if it’s against the Titans.

Raiders QB Geno Smith leads the NFL in interceptions with nine.

This is a hold-your-nose prediction, but I’ll take the road team.

PREDICTION: Titans +4.5 (-110)

Green Bay Packers vs. Cincinnati Bengals

The Bengals have traded for QB Joe Flacco, and while he just beat the Packers a few weeks ago as a member of the Browns, they were carried by their defence.

The Bengals don’t have a defence nearly as good as the Browns.

The Packers win big.

PREDICTION: Packers -14 (-110)

Tampa Bay Buccaneers vs. San Francisco 49ers

The 49ers primarily play Cover-3, and against that coverage, Buccaneers QB Baker Mayfield has a respectable completion percentage (67.2 per cent), but averages just 5.9 yards per attempt.

This is a tough game to predict, but I’ll lean toward the 49ers +3 in what I expect will be a back-and-forth game.

PREDICTION: 49ers +3 (-110)

Kansas City Chiefs vs. Detroit Lions

The Chiefs’ offence has woken up the last two weeks, but the Lions’ has been the best in the league all season, averaging 34.8 points per game.

The Chiefs are at home, which is a tough place to play, but I trust the Lions.

PREDICTION: Lions +2.5 (-110)

Atlanta Falcons vs. Buffalo Bills

The Bills’ odds to win the Super Bowl are +450, and that could change slightly after this game.

Buffalo and Atlanta allow the fewest passing yards per game. The Falcons allow the least at 135, and the Bills are just behind them at 154.

In what could be a lower-scoring game than expected based on the 49.5-point total, I’ll take the home team, plus the points.

PREDICTION: Falcons +4.5 (-110)

Washington Commanders vs. Chicago Bears

Bears QB Caleb Williams is just 2-8 on the road in his career, but the Bears have been improving.

Coming off the Week 5 bye, the Bears have won back-to-back games. Now, they’ll face the Commanders on the road, a team that plays Cover-3 more than anything else.

Versus Cover-3 this season, Williams has four touchdown passes.

PREDICTION: Bears +4.5 (-110)



from Sportsnet.ca
via i9bet

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